A new application about 1H-Indole-7-carbaldehyde

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A new series of gallic hydrazones containing an indole moiety was synthesized through the reaction of gallic hydrazide and different indole carboxaldehydes. Their antioxidant activities were determined on DPPH radical scavenging and inhibition of lipid peroxidation. The in-vitro cytotoxic activities of the compounds were evaluated against HCT-116 (human colon cancer cell line) and MCF-7 (estrogen-dependent human breast cancer cell line) by the MTT method. An attempt to correlate the biological results with their structural characteristics has been done. A limited positive structure activity relationship was found between cytotoxic and antioxidant activities. Gallic acid derivatives are naturally occurring compounds with interesting biological properties. Similarly, indolic compounds represent an important class of therapeutical agents in medicinal chemistry. A series of hybrid molecules incorporating these two pharmacophores has been synthesized and assessed for their antioxidant and cytotoxic activities. Copyright

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, Recommanded Product: 1074-88-0, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 1074-88-0

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles