Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: 3-Phenyl-1-Propanol, 122-97-4, Name is 3-Phenyl-1-Propanol, SMILES is OCCCC1=CC=CC=C1, belongs to indole-building-block compound. In a document, author is Xun, Wen, introduce the new discover.
Regio and Enantioselective Organocatalytic Friedel-Crafts Alkylation of 4-Aminoindoles at the C7-Position
A chiral phosphoric acid catalyzed highly regio- and enantioselective Friedel-Crafts alkylation at the indole C7-position was developed via the introduction of an alkylamine moiety at the C4-position of the indole ring. The methodology is applicable to a wide range of 4-aminoindoles and beta,gamma-unsaturated alpha-ketimino esters to furnish the corresponding C7-position functionalized chiral indole derivatives in high yields with moderate to excellent enantioselectivities. Furthermore, the alpha-ketimino ester moiety in the products is a versatile building block and enables many further transformations.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 122-97-4 is helpful to your research. Recommanded Product: 3-Phenyl-1-Propanol.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles