A new application about Methyl 2-(1H-indol-3-yl)acetate

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Synthetic Route of 1912-33-0, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1912-33-0

Synthetic Route of 1912-33-0, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.1912-33-0, Name is Methyl 2-(1H-indol-3-yl)acetate, molecular formula is C11H11NO2. In a Article£¬once mentioned of 1912-33-0

A short synthesis of the endogenous plant metabolite 7-hydroxyoxindole-3-acetic acid (7-OH-OxIAA) using simultaneous C-H borylations

Methyl indole-3-acetate undergoes two simultaneous iridium-catalysed borylations to deliver exclusively 2,7-diboronate, with the ligand 3,4,7,8-tetramethyl-1,10-phenanthroline (Me4Phen) pivotal in driving the diborylation to completion. Subsequent oxidation-hydrolysis of the diboronate provides methyl 7-hydroxyoxindole-3-acetate which upon hydrolysis of the ester delivers 7-OH-OxIAA, an antioxidant, endogenous metabolite of indole-3-acetic acid found in various types of corn. This route has an overall yield of 50%, involves a single chromatographic purification and is an efficient alternative to existing syntheses, made possible by executing simultaneous oxidations at the indole C2 and C7 sites.

One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Synthetic Route of 1912-33-0, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 1912-33-0

Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles