A new synthetic route of 132098-59-0

There is still a lot of research devoted to this compound(SMILES：C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Safety of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, and with the development of science, more effects of this compound(132098-59-0) can be discovered.

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Lourenco, Mirtha A. O.; Carneiro, Liliana; Mayoral, Alvaro; Diaz, Isabel; Silva, Ana R.; Ferreira, Paula researched the compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane( cas:132098-59-0 ).Safety of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane.They published the article 《Chiral periodic mesoporous copper(II) bis(oxazoline) phenylene-silica: A highly efficient and reusable asymmetric heterogeneous catalyst》 about this compound( cas:132098-59-0 ) in Journal of Catalysis. Keywords: chiral periodic mesoporous copper oxazoline phenylene silica; efficient reusable asym heterogeneous catalyst. We’ll tell you more about this compound (cas:132098-59-0).

We describe the preparation of an effective and reusable heterogeneous asym. catalyst. A novel chiral periodic mesoporous phenylene-silica containing high d. of bis(oxazoline) moieties is prepared by co-condensation method with 1,4-bis(triethoxysilyl)benzene. After copper(II) coordination, the material is extremely efficient on the kinetic resolution of the 1,2-diphenylethane-1,2-diol with persistent high enantioselectivities (91 – > 99%) and yields (46-43% in maximum 50% resolution) at least for five consecutive cycles. Characterization of the material after the catalytic experiments showed that the heterogeneous catalyst was very robust keeping the integrity of the structure.

There is still a lot of research devoted to this compound(SMILES：C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1)Safety of Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, and with the development of science, more effects of this compound(132098-59-0) can be discovered.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles