The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane, is researched, Molecular C19H18N2O2, CAS is 132098-59-0, about Enantioselective reduction of ketones with triethoxysilane catalyzed by chiral bis-oxazoline titanium complexes, the main research direction is arylethanol enantioselective preparation; arylbromoethanol enantioselective preparation; asym reduction aryl ketone bromoketone titanium bisoxazoline catalyst ethoxysilane.Electric Literature of C19H18N2O2.
Chiral bis-oxazoline titanium complexes prepared from a 2:1 mixture of C2 chiral bis-oxazolines such as I, BuLi and titanium salts, catalyze the enantioselective reduction of aryl ketones with triethoxysilane as a stoichiometric reductant. E.g., I is treated with 0.67 equivalent nBuLi at -78° in THF, warmed to 0°, and 0.5 equivalent TiF4 was added and the catalyst solution warmed to room temperature; triethoxysilane and 4-MeOC6H4COCH2Br were added and the mixture was stirred for 96h to give benzeneethanol (R)-II in 53% yield and 80% ee.
Although many compounds look similar to this compound(132098-59-0)Electric Literature of C19H18N2O2, numerous studies have shown that this compound(SMILES:C1(CC2=N[C@@H](C3=CC=CC=C3)CO2)=N[C@@H](C4=CC=CC=C4)CO1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles