Silver Mediated Banert Cascade with Carbon Nucleophiles was written by Alexander, Juliana R.;Kevorkian, Paul V.;Topczewski, Joseph J.. And the article was included in Organic Letters in 2021.Safety of 2-Methyl-6-nitro-1H-indole This article mentions the following:
The Banert cascade of propargylic azides was promoted by simple silver salts and the triazafulvene intermediate can be intercepted by carbon nucleophiles. Various indoles (>25 examples, up to 92% yield) and electron-rich heterocycles were effective. The Mayr nucleophilicity parameter (N) was found to correlate to the reaction efficiency, which enabled the formation of Csp3-Csp2 and Csp3-Csp3 bonds under otherwise identical conditions from structurally dissimilar nucleophiles. In the experiment, the researchers used many compounds, for example, 2-Methyl-6-nitro-1H-indole (cas: 3484-23-9Safety of 2-Methyl-6-nitro-1H-indole).
2-Methyl-6-nitro-1H-indole (cas: 3484-23-9) belongs to indole derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Safety of 2-Methyl-6-nitro-1H-indole
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles