Allred, Tyler K.; Shaghafi, Michael B.; Chen, Pan-Pan; Tran, Quan; Houk, K. N.; Overman, Larry E. published the artcile< Constructing Saturated Guanidinium Heterocycles by Cycloaddition of N-Amidinyliminium Ions with Indoles>, COA of Formula: C10H9NO, the main research area is guanidinium heterocycle preparation indole amidinyliminium regioselective stereoselective cycloaddition.
We report that structurally complex guanidinium heterocycles can be prepared in one step by regio- and stereoselective [4 + 2]-cycloadditions of N-amidinyliminium ions with indoles or benzothiophene. In contrast to reactions of these heterodienes with alkenes, d. functional theory (DFT) calculations show that these cycloadditions take place in a concerted asynchronous fashion. The [4 + 2]-cycloaddition of N-amidinyliminium ions (1,3-diaza-1,3-dienes) with indoles and benzothiophene are distinctive, as related [4 + 2]-cycloadditions of N-acyliminium ions (1-oxa-3-aza-1,3-dienes) are apparently unknown.
Organic Letters published new progress about [4+2] Cycloaddition reaction. 4771-48-6 belongs to class indole-building-block, and the molecular formula is C10H9NO, COA of Formula: C10H9NO.
Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles