Analyzing the synthesis route of 15861-24-2

As the paragraph descriping shows that 15861-24-2 is playing an increasingly important role.

15861-24-2, Indole-5-carbonitrile is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

15861-24-2, After introducing 5-cyanoindole, Boc2O, dichloromethane and DMAP into a 100 ml round-bottomed flask, the reaction medium is stirred at 0 C. under nitrogen for 2 hours. After disappearance of the starting cyanoindole, the reaction medium is poured into water and extracted with EtOAc. After drying and evaporating off the solvent, 1.7191 g of N-Boc-5-cyanoindole are obtained in the form of a yellowish powder. Rf (silica)=0.61; 7/3 cyclohexane/EtOAc. LC/MS m/z=242.

As the paragraph descriping shows that 15861-24-2 is playing an increasingly important role.

Reference£º
Patent; Aventis Pharma S.A.; US2004/242559; (2004); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles