16732-57-3, Ethyl 5-nitro-1H-indole-2-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
EXAMPLES Intermediate 1 5-Amino-1H-indole-2-carboxylic acid ethyl ester A solution of 5.1 g (22 mmol) ethyl 5-nitro-2-carboxylate indole in 300 ml THF was hydrogenated over PtO2 with 1 bar H2 for 2 h at room temperature. After filtration and evaporation the residue was purified over silica eluting with a mixture of ethyl acetate/heptane 4/1. After evaporation of the product fractions 4.28 g (96%) of the title compound was yielded as brown solid. MS (m/e): 205.3 (MH+, 100%)., 16732-57-3
The synthetic route of 16732-57-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Nettekoven, Matthias Heinrich; Plancher, Jean-Marc; Roche, Olivier; Rodriguez-Sarmiento, Rosa Maria; US2006/160855; (2006); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles