Analyzing the synthesis route of 168824-94-0

168824-94-0, The synthetic route of 168824-94-0 has been constantly updated, and we look forward to future research findings.

168824-94-0, tert-Butyl 3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Excess 1,3-dibromopropane and methyl 2-(4-hydroxyphenyl)acetate are reacted in ethanol to give compound 25.Compound 6 was dissolved in DMF,After pulling with NaH hydrogen,Add compound 25,The compound 26 is obtained by reacting at normal temperature.Compound 26 was dissolved in DCM.Join TFA,Reaction under ice bath conditions gave compound 27.

168824-94-0, The synthetic route of 168824-94-0 has been constantly updated, and we look forward to future research findings.

Reference£º
Patent; Second Military Medical University; Liu Na; Sheng Chunquan; Jiang Yanjuan; Tu Jie; Li Zhuang; Dong Guoqiang; Wu Shanchao; (31 pag.)CN108623585; (2018); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles