Analyzing the synthesis route of 245-08-9

As the paragraph descriping shows that 245-08-9 is playing an increasingly important role.

245-08-9, 5H-Pyrido[3,2-b]indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

One 100 mLThe flask Intermediate (4) (0.5 g, 1.005 mmol), delta-carboline(d-carboline)0.2 g (1.105mmol), CuI 24 mg (0.126 mmol), 1,10 phenanthroline (1,10 phenanthroline) 45mg (0.251 mmol), cesium carbonate (cesium carbonate, Cs2CO3) 0.7 g (2.010 mmol) and dimethylformamide (dimethylformamide, DMF) (40 mL) and mixed, and then,stirred for 12 hours at 120 ~ 130C. The reaction was cooled to room temperature and then terminated and purified by silica gel column chromatography to give compound (4-33) 0.2 g (Yield: 40%) of a white solid was obtained., 245-08-9

As the paragraph descriping shows that 245-08-9 is playing an increasingly important role.

Reference£º
Patent; WS Co.,Ltd; Ko, Byung Soo; Oh, Yu Jin; (61 pag.)KR2016/50891; (2016); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles