245-08-9, 5H-Pyrido[3,2-b]indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
o a 250 ml two-necked flask was added delta -carboline (15 g, 89 mmol), 1-bromo-4-iodobenzene,, CuI (1.1 g, 5.79 mmol), 1,10-phenanthroline (2 g, 11.13 mmol), K3PO4 (47 g, 220 mmol)(Dioxane, 300 ml) were put together and refluxed at 80 to 100 C under nitrogen for 24 hours. After the reaction was completed, methylene chloride(MC) and Celite filter. The filtered solution was distilled under reduced pressure, then extracted with MC and distilled waterAll. The extracted MC layer was extracted with MgSO4 and the solvent was removed by distillation under reduced pressure to obtain a yellow solid. This solidThe white solid (2) was isolated (18.7 g, 65%) using the Column Chromatography method., 245-08-9
As the paragraph descriping shows that 245-08-9 is playing an increasingly important role.
Reference£º
Patent; WS Co., Ltd; Koh, Byung Soo; Kim, Kyu Sik; Kwak, Tae Young; Oh, Yu Jin; (36 pag.)KR2015/9205; (2015); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles