26340-49-8, 2-Iodo-1H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To the solution of iodoindole 6 (200 mg, 0.82 mmol) in DMF (2.8 mL) at 0 C was added powderedKOH (70 mg, 1.24 mmol). The heterogeneous mixture was stirred at 0 C for 5 min and treated withBnBr (154 mg, 0.90 mmol). After stirring at 0 C for 10 min, the reaction mixture was diluted with Et2O(15 mL) and quenched with brain (10 mL). The layers were separated and the aqueous layer was6extracted with Et2O (1 x 15 mL). The organic layers were combined, dried over Na2SO4, andconcentrated in vacuo. The residue was purified by flash chromatography (silica gel, hexane/AcOEt =50:1) to afford 2d (267 mg, 97% yield) as a white solid., 26340-49-8
The synthetic route of 26340-49-8 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Miyamoto, Hiroshi; Hirano, Tomohiro; Okawa, Yoichiro; Nakazaki, Atsuo; Kobayashi, Susumu; Tetrahedron; vol. 69; 45; (2013); p. 9481 – 9493;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles