271-34-1, 5-Azaindole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of triethylamine (0.65 ml, 4.66 mmol) and 5-azaindole (1.00 g, 8.46 mmol) in MeCN (20 ml) stirring at 0 00 was added di-teit-butyl dicarbonate (0.97 ml,4.23 mmol) dropwise under nitrogen with stirring. The reaction was allowed to warm to room temperature and left to stir over the weekend. Further di-teit-butyl dicarbonate (0.97 ml, 4.23 mmol) was added and stirring continued for 6 hours. The reaction mixture was concentrated under reduced pressure and the oil obtained taken up in DCM and washed with water. The mixture was passed through a hydrophobic frit and solvent removed under reduced pressure to afford teit-butyl pyrrolo[3,2-c]pyridine-1-carboxylate (P62) (1.76 g), LCMS ES 219 [M+H], Rt = 1.19 mins (Generic Basic Method)., 271-34-1
The synthetic route of 271-34-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; CANCER RESEARCH TECHNOLOGY LIMITED; PUGLIESE, Angelo; FRANCIS, Stuart; MCARTHUR, Duncan; SIME, Mairi; BOWER, Justin; BELSHAW, Simone; (315 pag.)WO2019/34890; (2019); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles