31241-19-7, 5-Methoxy-2,3,3-trimethyl-3H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
1.70 g (9.00 mmol) of 2,3,3-trimethyl-6-methoxyindole 1 were weighed and 2.61 g (18.0 mmol) of 2-formylbenzopyrrole was weighed and 0.15 L of a toluene solution was measured.Take organic acid 0.24mL, 0.30mL organic base were heated and stirred, refluxed at 120 for 2 hours, dried and filtered to give a yellow compound 3.Take 1.99 g (4.50 mmol) of the above compound 3, take 35 mL of toluene solution and 2.80 mL of triethylamine, add 2.10 mL (17.50 mmol) of boron trifluoride etherate solution dropwise with stirring under electromagnetic agitation and raise the temperature to 120 C.,Condensing reflux 8 hours, TLC point plate test, the product was washed, extracted, dried, rotary evaporation, filtered to give compound 4:, 31241-19-7
31241-19-7 5-Methoxy-2,3,3-trimethyl-3H-indole 11095392, aindole-building-block compound, is more and more widely used in various fields.
Reference：
Patent; China Three Gorges University; Zhang Nuonuo; Li Yujiao; Yan Jiaying; Cheng Kai; Li Dejiang; (12 pag.)CN105925004; (2016); A;,
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