With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.700-06-1,Indole-3-Carbinol,as a common compound, the synthetic route is as follows.
In order to confirm the antioxidant activity of the compounds, a DPPH method was employed. DPPH (l,l-diphenyl-2-picrylhydrazyl) is a chromogenic radical and thus, can be used to directly confirm the radical scavenging activity of the samples. The samples were dissolved in 4 ml of distilled water or solvent (methanol) and then, mixed well with 1 ml of 100 muM DPPH. Subsequently, the samples were incubated at room temperature for 30 minutes. The absorbance of the remaining DPPH was measured at 517 nm. As a blank of the present experiment, distilled water or solvent was used, and as a control, an experimental group composed only of DPPH in distilled water or solvent without the sample was used. Further, vitamin C was used as a positive control. As a result, the antioxidant activity was expressed as percentages of the absorbance of each hydrolysate relative to the absorbance of control, as calculated by the following equation 1.[81][82] (Experimental Equation 1)[83]RSAW = Ab5 f hydfKylate chi l00 Abs of Control[84] (RSA: Radical Scavenging Activity)[85]
700-06-1 Indole-3-Carbinol 3712, aindole-building-block compound, is more and more widely used in various.
Reference£º
Patent; BIOSPECTRUM, INC.; WO2008/72941; (2008); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles