The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1,4-Dibromobutane( cas:110-52-1 ) is researched.Category: indole-building-block.Deng, Ke-Zuan; Jia, Wen-Liang; Angeles Fernandez-Ibanez, M. published the article 《Selective Para-C-H Alkynylation of Aniline Derivatives by Pd/S,O-Ligand Catalysis》 about this compound( cas:110-52-1 ) in Chemistry – A European Journal. Keywords: alkynyl dibenzylaniline preparation; silyl alkynyl iodide dibenzylaniline alkynylation regioselective; C−H activation; S,O-ligand; alkynylation; aniline; palladium. Let’s learn more about this compound (cas:110-52-1).
Herein, authors report a nondirected para-selective C-H alkynylation of aniline derivatives by a Pd/S,O-ligand-based catalyst. The reaction proceeds under mild conditions and is compatible with a variety of substituted anilines. The scalability and further derivatizations of the alkynylated products have been also demonstrated.
Different reactions of this compound(1,4-Dibromobutane)Category: indole-building-block require different conditions, so the reaction conditions are very important.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles