A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, category: indole-building-block, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 10075-52-2, Name is 5-Bromo-1-methyl-1H-indole, molecular formula is C9H8BrN. In a Patent, authors is ，once mentioned of 10075-52-2
The invention discloses a method of optically active 3 – substituted indole derivative and its chemical synthesis method and application, the optically active 3 – substituted indole derivative comprises the formula (Ia) shown in formula (Ib) structure. First of all, in order to diazo compounds, indole derivatives and alpha, beta – unsaturated aqueous raw material, in order to Molecular sieve as water-absorbing agent, a metal catalyst, the chiral diaryl prolinol silyl ether and substituted benzoic acid as catalyst, in order to organic solvent as a solvent, in the 0 – 40 C under after a step reaction to obtain the target product. The invention synthetic method has high-atomic economic, high selectivity, the advantage of high yield, and the mild reaction conditions, simple and safe operation. The invention of a pair of optically active 3 – substituted indole derivatives with high enantio-selectivity, and has biological activity, is suitable for the anti-tumor pharmaceutical preparation application. (by machine translation)
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 10075-52-2, help many people in the next few years.Quality Control of: 5-Bromo-1-methyl-1H-indole
Reference：
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles