527-60-6, Name is 2,4,6-Trimethylphenol, molecular formula is C9H12O, belongs to indole-building-block compound, is a common compound. In a patnet, author is Wang, Xu, once mentioned the new application about 527-60-6, SDS of cas: 527-60-6.
Development of an imidazole salt catalytic system for the preparation of bis(indolyl)methanes and bis(naphthyl)methane
Imidazolium salts are shown to catalyze the rapid room temperature reaction of indoles or naphthol with aldehydes to provide bis(indolyl) methanes or bis(naphthol) methane in excellent yields and the reaction proceeds optimally in dichloromethane with no base additives. The reaction exhibits a broad substrate tolerance and occurs through nucleophilic activation of the indoles and naphthols through a cation-pi interaction.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles