Related Products of 94-26-8, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 94-26-8, Name is Butyl 4-hydroxybenzoate, SMILES is O=C(OCCCC)C1=CC=C(O)C=C1, belongs to indole-building-block compound. In a article, author is Leonel, Guilherme, introduce new discover of the category.
The intramolecular electrophilic cyclization of 3-organoselanyl-2-alkynylindoles providing the synthesis of 3-iodo-selenophene-fused indoles is reported herein. The strategy was extended to the preparation of 3-iodo-thiophene-fused indoles in a one-pot iodine-promoted thiolation of 2-alkynylindoles, followed by an electrophilic cyclization sequence. Besides, the synthesis of 3-butylselanyl-selenophene-fused indoles from 3-butylselanyl-2-alkynylindoles was also developed using iron(III) chloride and dibutyl diselenide to promote the cyclization and functionalization of the heterocycle. The identification of the alkyl halide intermediate afforded evidence to the proposed mechanism, which indicated that the reactions proceed through the formation of an iodonium ion, followed by a selenium 5-endo-dig cyclization, to afford the indole derivatives. The 3-iodo-selenonophene-fused indoles prepared were applied as substrates in copper-catalyzed cross-coupling reactions with thiols to give the Ullmann type products in good yields.
Related Products of 94-26-8, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 94-26-8.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles