SDS of cas: 99-93-4. In 2020 J AM CHEM SOC published article about PALLADIUM-CATALYZED 1,4-DIFUNCTIONALIZATION; LIGHT PHOTOREDOX CATALYSIS; CROSS-COUPLING REACTIONS; CARBON BOND FORMATION; DOMINO REACTIONS; HECK REACTION; C-C; CONJUGATED DIENES; ATOM-TRANSFER; HALIDES in [Huang, Huan-Ming; Bellotti, Peter; Pflueger, Philipp M.; Schwarz, J. Luca; Glorius, Frank] Westfalische Wilhelms Univ Munster, Organ Chem Inst, D-48149 Munster, Germany; [Heidrich, Bastian] Westfalische Wilhelms Univ Munster, MEET Battery Res Ctr, Inst Phys Chem, D-48149 Munster, Germany in 2020, Cited 139. The Name is 4′-Hydroxyacetophenone. Through research, I have a further understanding and discovery of 99-93-4.
Developing efficient and selective strategies to approach complex architectures containing (multi)stereogenic centers has been a long-standing synthetic challenge in both academia and industry. Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks. Unfortunately, carrying out cascade Heck-type reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoidable beta-hydride elimination. Herein, we show that a modular, practical, and general palladium-catalyzed, radical three-component coupling can indeed overcome the aforementioned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light. Selective 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employing different commercially available nitrogen-, oxygen-, sulfur-, or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 a). Sequential C(sp(3))-C(sp(3)) and C-X (N, O, S) bonds have been constructed efficiently with a broad scope and high functional group tolerance. The flexibility and versatility of the strategy have been illustrated in a gram-scale reaction and streamlined syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficult to access via currently established methods.
About 4′-Hydroxyacetophenone, If you have any questions, you can contact Huang, HM; Bellotti, P; Pfluger, PM; Schwarz, JL; Heidrich, B; Glorius, F or concate me.. SDS of cas: 99-93-4
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles