Electric Literature of 13739-02-1, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C–H bond functionalisation has revolutionised modern synthetic chemistry. 13739-02-1, Name is Diacerein, SMILES is O=C(C1=C2C(OC(C)=O)=CC=C1)C3=CC(C(O)=O)=CC(OC(C)=O)=C3C2=O, belongs to indole-building-block compound. In a article, author is Das, Sukanya, introduce new discover of the category.
A sequential acidic ionic liquid catalyzed one pot approach was conducted for preparation of 3-substituted indoles starting from in situ generated chalcones involving Claisen-Schmidt condensation of substituted aromatic aldehydes with acetophenone followed by Michael-like addition of indoles to these chalcones under solvent-free thermal reactions. For this purpose, some new and some reported Bronsted acidic ionic liquids, 2-alkyl-1, 3-disulfoimidazolium carboxylate [RDSIM][X] (where R= Me & Et and X=CH3COO-, CCl3COO-, CF3COO-), were analyzed to compare their Bronsted acidic strength and thermal stabilities. From this investigation, 2-methyl-1, 3-disulfoimidazolium trifluoroacetate [MDSIM][CF3COO] and 2ethyl-1,3-disulfoimidazolium trifluoroacetate [EDSIM][CF3COO] were determined as efficient ionic liquid catalysts for study of the two-step one pot synthesis of 3-substituted indoles.
Electric Literature of 13739-02-1, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 13739-02-1 is helpful to your research.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles