A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Safety of 3-Phenyl-1H-indole, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1504-16-1, Name is 3-Phenyl-1H-indole, molecular formula is C14H11N. In a Article, authors is Kakefuda, Akio,once mentioned of 1504-16-1
In the search for a novel class of selective antagonists for the human V1A receptor, high-throughput screening (HTS) of the Yamanouchi chemical library using CHO cells expressing the cloned human V1A (hV1A) receptor led to the discovery of 5-(4-biphenyl)-4-(2-methoxyphenyl)-3-methyl-1,2,4-triazole (3) which possessed the novel 4,5-diphenyl-1,2,4-triazole structure. Subsequent structure-activity relationships studies on a series of the 4,5-diphenyl-1,2,4-triazole derivatives related to 3 revealed that the 4,5-diphenyl-1,2,4-triazole structure played an essential role in exerting high affinity for the hV1A receptor and that introduction of a basic amine moiety to the methoxy part of the 4-phenyl ring was effective in the improvement of both affinity for the hV1A receptor and selectivity versus the hV2 receptor. Compound 3 and the 2-(morphorino)ethoxy derivative (11b) were shown to be antagonists for the hV1A receptor, from their effects on AVP-induced [Ca2+]i response in CHO cells expressing the hV1A receptor.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 1504-16-1, help many people in the next few years.Safety of 3-Phenyl-1H-indole
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles