Let¡¯s face it, organic chemistry can seem difficult to learn, Name: 3,5-Dibromo-2-hydroxybenzaldehyde, Especially from a beginner¡¯s point of view. Like 90-59-5, Name is 3,5-Dibromo-2-hydroxybenzaldehyde, molecular formula is indole-building-block, belongs to indole-building-block compound. In a document, author is Seyitdanlioglu, Pinar, introducing its new discovery.
An efficient water-mediated synthetic route for the alkylation of heteroarenes
An efficient synthetic route has been described for the alkylation of 1H-indole, 1H-benzimidazole, and 1H-benzotriazole. This approach features the alkylation of heteroaromatics through in situ generated enones from ketonic Mannich bases under metal-free conditions. A series of alkylated heteroaromatics have been synthesized via the K10 catalyzed alkylation reactions of these heteroaromatics with a variety of ketonic Mannich bases. Environmentally benign K10 catalyst, water-mediated mild reaction conditions, and the efficient synthesis of alkylated products are the advantages of this alkylation method.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles