Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 99-50-3, Name is Protocatechuic acid, molecular formula is , belongs to indole-building-block compound. In a document, author is Zhou, Chun-Ni, COA of Formula: C7H6O4.
Synthesis of Terminal Vinylindoles via Rh-III-Catalyzed Direct C-H Alkenylation with Potassium Vinyltrifluoroborate
An efficient Rh-III-catalyzed direct C2-alkenylation of indoles using readily available potassium vinyltrifluoroborate under mild conditions has been developed. This protocol features wide substrate scope and excellent functional group compatibility, enabling a facile access to diverse terminal vinylindoles in moderate to good yields. Furthermore, the C2-alkenylated indole can be easily transformed into 9H-carbazole through a ring-closing metathesis/aromatization cascade.
If you are hungry for even more, make sure to check my other article about 99-50-3, COA of Formula: C7H6O4.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles