In an article, author is Miyazaki, Yusuke, once mentioned the application of 51298-62-5, HPLC of Formula: C7H16ClN5O4, Name is L-NAME Hydrochloride, molecular formula is C7H16ClN5O4, molecular weight is 269.69, MDL number is MFCD00039052, category is indole-building-block. Now introduce a scientific discovery about this category.
Nickel-Catalyzed Asymmetric Friedel-Crafts Propargylation of 3-Substituted Indoles with Propargylic Carbonates Bearing an Internal Alkyne Group
The nickel-catalyzed highly enantioselective Friedel Crafts propargylation of 3-substituted indoles with propargylic carbonates bearing an internal alkyne group was developed. A wide array of the propargylic carbonates as well as 3-substituted indoles can be applicable to the asymmetric nickel catalysis, providing the corresponding chiral C-3 propargylated indolenine derivatives bearing two vicinal chiral centers in up to 89% yield with up to >99% ee and 94:6 dr (24 examples).
If you are interested in 51298-62-5, you can contact me at any time and look forward to more communication. HPLC of Formula: C7H16ClN5O4.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles