A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, 1011-65-0, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 1011-65-0, Name is Methyl 1H-indole-5-carboxylate, molecular formula is C10H9NO2. In a Article, authors is Sanz, Roberto£¬once mentioned of 1011-65-0
Bronsted acid catalyzed alkylation of indoles with tertiary propargylic alcohols: Scope and limitations
Direct alkylation of indoles with a wide variety of tertiary propargylic alcohols under Bronsted acid catalysis conditions has been studied. A general and environmentally friendly method for the synthesis of 3-propargylated indoles with quaternary carbon atoms at their propargylic positions has been developed. The reactions are highly regioselective with regard both to the indole and to the alkynol components. Only with N-unsubstituted 2-arylindoles do competitive SN? reactions take place to afford 3-dienyl- or 3-allenylindoles, depending on the alkynol moiety. The reactions were carried out in air with undried solvents, and water was the only side product. Treatment of indoles with tertiary propargylic alcohols in the presence of Bronsted acid catalysts provided 3-propargylindoles with quaternary centers at their propargylic positions. In addition, 3-dienyl- and 3-allenylindoles could also be obtained with convenient substitution in the indole and alkynol components. The reactions needed no special precautions, and water was the only side product. Copyright
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1011-65-0
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Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles