Awesome Chemistry Experiments For 1143532-39-1

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In an article, author is Dotsenko, V. V., once mentioned the application of 1143532-39-1, Name is AZD5363, molecular formula is C21H25ClN6O2, molecular weight is 428.9152, MDL number is MFCD22628785, category is indole-building-block. Now introduce a scientific discovery about this category, Product Details of 1143532-39-1.

Sequential reaction of indole-3-carbaldehyde with cyanothioacetamide and KOH led to the formation of potassium 6-amino-4-(1H-indol-3-yl)-3,5-dicyanopyridine-2-thiolate. S-Alkylation of the latter afforded new functional derivatives of 3-(pyridine-4-yl)-1H-indole and 4-(1H-indol-3-yl)-thieno[2,3-b]pyridine.

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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles