Safety of 4-Methoxybenzaldehyde. Authors Buntasana, S; Seankongsuk, P; Vilaivan, T; Padungros, P in WILEY-V C H VERLAG GMBH published article about in [Buntasana, Supanat; Padungros, Panuwat] Chulalongkorn Univ, Dept Chem, Fac Sci, Green Chem Fine Chem Prod STAR, Phayathai Rd, Bangkok 10330, Thailand; [Seankongsuk, Pattarakiat; Vilaivan, Tirayut] Chulalongkorn Univ, Fac Sci, Dept Chem, Organ Synth Res Unit, Phayathai Rd, Bangkok 10330, Thailand in 2021.0, Cited 96.0. The Name is 4-Methoxybenzaldehyde. Through research, I have a further understanding and discovery of 123-11-5
Ozonolysis is an oxidative cleavage reaction of alkenes with ozone that is indispensable and has found many applications in organic synthesis. However, dedicated laboratory ozone generators are quite expensive equipment and may not be affordable by many laboratories. Recently, low-cost ozone disinfectors have become more common as a household appliance. Herein, we demonstrate the applicability of a household ozone disinfector, which can produce ozone in the order of 10 mmol/h, as alternative equipment for the laboratory scale ozonolysis of alkenes. The ozonolysis of 14 styrene derivatives bearing electron-donating and electron-withdrawing groups on aromatic rings including those with alpha- and beta-substituents, as well as 8 natural products containing olefinic moieties were investigated. Ozonolysis of these alkenes at millimole scales proceeded to completion within 30-40 minutes and the carbonyl products were obtained in 68% to quantitative yields. Preparative-scale ozonolysis of 4-methoxystyrene (6.17 g, 46 mmol) was also demonstrated. The reaction proceeded smoothly to yield 4-anisaldehyde in 92% yield, which was subsequently converted to p-anisaldehyde dimethyl acetal in 66% yield. This work presents household ozone disinfector as an affordable, compact size, and practical synthetic equipment that does not require extra modification. Thus, the household ozone disinfector offers convenient access to ozonolysis or other reactions involving ozone for low-budget laboratories.
About 4-Methoxybenzaldehyde, If you have any questions, you can contact Buntasana, S; Seankongsuk, P; Vilaivan, T; Padungros, P or concate me.. Safety of 4-Methoxybenzaldehyde
Reference:
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,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles