Cobalt-Catalyzed One-Step Access to Pyroquilon and C-7 Alkenylation of Indoline with Activated Alkenes Using Weakly Coordinating Functional Groups was written by Banjare, Shyam Kumar;Biswal, Pragati;Ravikumar, Ponneri Chandrababu. And the article was included in Journal of Organic Chemistry in 2020.Category: indole-building-block This article mentions the following:
A new strategy for the C(7)-H functionalization of indoline derivatives using first-row transition-metal cobalt was demonstrated wherein the pivaloyl group acts as a weakly coordinating directing group. Biol. important pyroquilon(tetrahydropyroquinolinone) derivatives were synthesized in a one-pot manner through selective C(7)-H functionalization and concomitant cyclization. In this process, aromatic C-H and amidic C-N bonds were cleaved and new C-C and C-N bonds were formed in a step-economical fashion. Further, selective C(7)-H alkenylation of indoline derivatives was also accomplished using activated alkenes by varying the reaction conditions. In the experiment, the researchers used many compounds, for example, 6-Nitro-1H-indole (cas: 4769-96-4Category: indole-building-block).
6-Nitro-1H-indole (cas: 4769-96-4) belongs to indole derivatives. The indole subunit is an almost ubiquitous component of biologically active natural products, and its study has been the focus of research for decades. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Category: indole-building-block
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Indole alkaloid derivatives as building blocks of natural products from闂佽壈浜崹淇沜illus thuringiensis闂佽壈浜粋鍧闂佽壈浜崹淇沜illus velezensis闂佽壈浜粋鍧 their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles