Visible-Light-Induced Controlled Oxidation of N-Substituted 1,2,3,4-Tetrahydroisoquinolines for the Synthesis of 3,4-Dihydroisoquinolin-1(2H)-ones and Isoquinolin-1(2H)-ones was written by Bansode, Ajay H.;Suryavanshi, Gurunath. And the article was included in Advanced Synthesis & Catalysis in 2021.Synthetic Route of C14H11NO This article mentions the following:
A visible light-rose bengal-TBHP mediated, controlled oxidation of N-substituted 1,2,3,4-tetrahydroisoquinolines I (R = Me, 4-bromophenyl, thiophen-3-yl, etc.; R1 = H, Br; R2 = H, I) is developed for the synthesis of 3,4-dihydroisoquinolin-1(2H)-ones II and isoquinolin-1(2H)-ones III. The present method feature’s a broad substrate scope and good functional group tolerances, and the products II and III are prepared in good to excellent yields. The developed methodol. further demonstrated in the synthesis of isoindolo[2,1-b] isoquinolin-5(7H)-one (topoisomerase-I inhibitor). In the experiment, the researchers used many compounds, for example, 2-Phenylisoindolin-1-one (cas: 5388-42-1Synthetic Route of C14H11NO).
2-Phenylisoindolin-1-one (cas: 5388-42-1) belongs to indole derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered.Indole was synthesized in moderate yield via an o-naphthoquinone catalyzed tandem cross-coupling of substituted aniline and benzylamine under aerobic oxidation conditions.Synthetic Route of C14H11NO
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles