On May 31, 2008, Baumann, Thomas; Baechle, Michael; Hartmann, Caroline; Brase, Stefan published an article.Electric Literature of 79815-20-6 The title of the article was Thermal effects in the organocatalytic asymmetric α-amination of disubstituted aldehydes with azodicarboxylates: a high-temperature organocatalysis. And the article contained the following:
This article describes the thermally accelerated organocatalytic α-amination of disubstituted aldehydes with azodicarboxylates under microwave conditions. Compared to the results previously obtained at room temperature, both yield and enantioselectivity could be significantly increased. Employing microwave irradiation resulted in a considerably reduced reaction time. Therefore, this improved protocol allows the fast and efficient synthesis of α,α-disubstituted amino aldehydes and provided the best results for the α-amination of disubstituted aldehydes to date. The experimental process involved the reaction of H-Idc-OH(cas: 79815-20-6).Electric Literature of 79815-20-6
The Article related to thermal organocatalysis asym amination disubstituted aldehyde azodicarboxylate temperature, Physical Organic Chemistry: Stereochemistry and Stereochemical Relationships, Including Conformational Inversions and Rotational Isomerization and other aspects.Electric Literature of 79815-20-6
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles