Substituted oxindoles. I. The preparation and spectral characteristics of some simple oxindole derivatives was written by Beckett, Arnold H.;Daisley, R. W.;Walker, J.. And the article was included in Tetrahedron in 1968.Reference of 20870-91-1 This article mentions the following:
A series of oxindole derivatives substituted in the aromatic ring and their 1-Me homologs was prepared The effects of position and nature of substituents on the ir, N.M.R. and uv spectra were investigated. Evidence is presented which indicates the presence of an intermol. H bond in solutions of oxindole and certain 1-substituted derivatives A relation between the Hammett 闂?constant of substituents and the carbonyl frequencies of these oxindoles is reported. In the experiment, the researchers used many compounds, for example, 5-Amino-1-methyl-2-oxoindoline (cas: 20870-91-1Reference of 20870-91-1).
5-Amino-1-methyl-2-oxoindoline (cas: 20870-91-1) belongs to indole derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Reference of 20870-91-1
Referemce:
Indole alkaloid derivatives as building blocks of natural products from闂佽壈浜崹淇沜illus thuringiensis闂佽壈浜粋鍧闂佽壈浜崹淇沜illus velezensis闂佽壈浜粋鍧 their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles