Benghiat, Eric’s team published research in Synthesis in 1982-12-31 | CAS: 5654-92-2

Synthesis published new progress about Amino acids Role: SPN (Synthetic Preparation), PREP (Preparation). 5654-92-2 belongs to class indole-building-block, name is N,N-Dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine, and the molecular formula is C10H13N3, Safety of N,N-Dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine.

Benghiat, Eric published the artcilePreparation of S-(3-indolylmethyl) derivatives of mercapto amino acids, Safety of N,N-Dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine, the main research area is indolylmethyl mercapto amino acid; cysteine indolylmethyl; homocysteine indolylmethyl.

Title compounds I (X = CH, R = H, Me; R1 = H, Me; X = N, R = R1 = H; n = 1, 2) were prepared by treating indoles II (X = CH, R = H, Me; X = N, R = R1 = H; R2 = NMe2; X = CH, R = Me, R1 = H, Me, R2 = N+Me3 I-) with DL-HS(CH2)nCH(NH2)CO2H in aqueous NaOH. I (n = 2) were also prepared by treating the appropriate II with thialactone DL-III. I (X = CH, R = R1 = H, n = 2) was also prepared by treating II (X, R, R1 = same, R2 = N+Me3 I-) with DL-[HO2CCH(NH2)CH2CH2S].

Synthesis published new progress about Amino acids Role: SPN (Synthetic Preparation), PREP (Preparation). 5654-92-2 belongs to class indole-building-block, name is N,N-Dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine, and the molecular formula is C10H13N3, Safety of N,N-Dimethyl-1-(1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine.

Referemce:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles