In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Ligand Scaffold Optimization of a Supramolecular Hydrogenation Catalyst: Analyzing the Influence of Key Structural Subunits on Reactivity and Selectivity, published in 2012-12-07, which mentions a compound: 132098-59-0, mainly applied to ligand scaffold optimization supramol hydrogenation catalyst; asymmetric catalysis; asymmetric hydrogenation; rhodium-catalyzed; self-assembled ligands; self-assembly; supramolecular catalysis, Application of 132098-59-0.
Results are reported for the catalytic asym. hydrogenation of two prototypical substrates with a series of more than 150 closely related supramol. catalysts differing in only their ligand/catalyst scaffold. These modular catalysts are constructed from four subunits and vary widely in their reactivity (no reaction to quant. yield) and enantioselectivity (racemic to 96% enantiomeric excess (ee)). Anal. of the ligand/catalyst scaffold optimization data reveals how each subunit contributes to the effectiveness of the modular supramol. catalyst. The results suggest that a balance between key elements of rigidity and flexibility is required for the successful catalysts and, moreover, that this balance is required to enable effective fine-tuning via catalyst scaffold optimization.
Different reactions of this compound(Bis((S)-4-phenyl-4,5-dihydrooxazol-2-yl)methane)Application of 132098-59-0 require different conditions, so the reaction conditions are very important.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles