16096-32-5, 4-Methyl-1H-indole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(1) 4-methylindole 0.5 mmol, sodium trifluoromethanesulfinate 1.0 mmol,Triphosaldehyde 1.0 mmol was added to 3 mL of acetonitrile, and the reaction was stirred for 2 hours under ice bath.(2) After the reaction was completed, the reaction was quenched by adding 10 mL of a 5% aqueous NaOH solution.Extract twice with ethyl acetate (15 mL ¡Á 2), wash once with saturated brine.Ethyl acetate was distilled off under reduced pressure. Column chromatography gave the product as a pale yellow solid.The yield was 76%.
16096-32-5 4-Methyl-1H-indole 85282, aindole-building-block compound, is more and more widely used in various.
Reference£º
Patent; Lishui College; Yuan Yanqin; Guo Shengrong; Yang Minghua; (28 pag.)CN108586312; (2018); A;,
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