Brief introduction of 16136-52-0

16136-52-0, 16136-52-0 4-Cyanoindole 3817602, aindole-building-block compound, is more and more widely used in various fields.

16136-52-0, 4-Cyanoindole is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: The calcium or magnesium salt (0.025 mmol, 10 mol%) and Michael acceptor (0.25 mmol) were dissolved in solvent (0.5 mL), and the mixture was stirred at r.t. for 30 min in a glass vial. The aromatic compound (0.5 mmol) was added and the reaction was stirred at the temperature indicated in Tables 2-9; reaction progress was monitored by TLC. When the reaction was complete, the solvent was evaporated under reduced pressure. The crude residue was purified by column chromatography to afford the product.

16136-52-0, 16136-52-0 4-Cyanoindole 3817602, aindole-building-block compound, is more and more widely used in various fields.

Reference£º
Article; Feofanov, Mikhail N.; Anokhin, Maxim V.; Averin, Alexei D.; Beletskaya, Irina P.; Synthesis; vol. 49; 22; (2017); p. 5045 – 5058;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles