With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.16732-57-3,Ethyl 5-nitro-1H-indole-2-carboxylate,as a common compound, the synthetic route is as follows.
Commercially available ethyl 5-nitro-1H-indole-2-carboxylate (1.00 g, 4.27 mmol) of methanol (20 mL) solution Palladium-carbon (907 mg) in addition, stirred for three hours under a hydrogen atmosphere. Celite filtration reaction and be evaporated and the residue that obtained the title compound (876 mg, 100%).
16732-57-3, The synthetic route of 16732-57-3 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; DAINIPPON SUMITOMO PHARMA CO LTD; IKUMA, YOHEI; IWATA, MASAKADO; NAKAI, YOSHIO; (62 pag.)JP2015/13821; (2015); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
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