Chemistry, like all the natural sciences, Formula: C7H7FO2S, begins with the direct observation of nature¡ª in this case, of matter.329-98-6, Name is Phenylmethanesulfonyl fluoride, SMILES is O=S(CC1=CC=CC=C1)(F)=O, belongs to indole-building-block compound. In a document, author is Alexy, Eric J., introduce the new discover.
Palladium-catalyzed enantioselective decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates
The first enantioselective palladium-catalyzed decarboxylative allylic alkylation of fully substituted N-acyl indole-derived enol carbonates forming acyclic all-carbon quaternary stereocenters is reported. Excellent yields up to 99% and enantioselectivities up to 98% ee are obtained through the use of a new electron-deficient phosphinoxazoline (PHOX) ligand. Control of substrate enolate geometry is crucial for high selectivity. The obtained a-quaternary N-acyl indoles are formal ester equivalents, and represent a useful handle for further synthetic transformations.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 329-98-6. Formula: C7H7FO2S.
Reference:
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles