Synthetic Route of 599-64-4, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 599-64-4, Name is 4-(2-Phenylpropan-2-yl)phenol, SMILES is OC1=CC=C(C(C)(C2=CC=CC=C2)C)C=C1, belongs to indole-building-block compound. In a article, author is Liu, Ruixing, introduce new discover of the category.
Rhodium(III)-Catalyzed Cross Coupling of Sulfoxonium Ylides and 1,3-Diynes to Produce Naphthol-Indole Derivatives: An AreneorthoC-H Activation/Annulation Cascade
Synthesis of naphthol-indoles starting from easily available 1,3-diynes and sulfoxonium ylides via Rh-III-catalyzed C-H activation/hydroamination cascade process in a one pot manner has been developed. The reaction proceeds through a Rh-III-catalyzed areneorthoC-H activation and silver-catalyzed hydroamination cascade to afford a variety of C2 position functionalized indoles in good yields with broad substrate scope and good functional group tolerance.
Synthetic Route of 599-64-4, Consequently, the presence of a catalyst will permit a system to reach equilibrium more quickly, but it has no effect on the position of the equilibrium as reflected in the value of its equilibrium constant.I hope my blog about 599-64-4 is helpful to your research.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles