7254-19-5, 5-Bromo-1H-indole-2-carboxylic acid is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,7254-19-5
Example 20 Preparation of 4S-[(5-bromo-1H-indole-2-carbonyl)-amino]-5-(2-oxo-pyrrolidin-3S-yl)-pent-2-enoic Acid Compound 20 was prepared according to the method of Example 1, using 5-bromo-2-indolecarboxylic acid. 1H NMR (CDCl3) delta9.94 (1H, s), 8.94 (1H, d, J=5.9), 7.73 (1H, s), 7.30 (2H, s), 7.07 (1H, d, J=1.8) 6.95 (1H, dd, J=15.6, 5.3), 6.42 (1H, s), 6.03 (1H, dd, J=15.6, 1.4), 4.80-4.65 (1H, m), 4.17 (2H, q, J=7.1), 3.45-3.35 (2H, m), 2.70-2.55 (1H, m), 2.50-2.38 (1H, m), 2.15-1.78 (3H, m), 1.27 (3H, t, J=7.1). MS (FAB) 448.0858 (MH+, calcd 448.0872), 470 (MNa+).
The synthetic route of 7254-19-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Johnson, Jr., Theodore O.; Chu, Shao Song; Eastman, Brian Walter; Hua, Ye; Luu, Hiep The; Reich, Siegfried Heinz; Skalitzky, Donald James; Yang, Yi; Hendrickson, Thomas F.; Chan, Fora P.; US2002/61916; (2002); A1;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles