90923-75-4, 1-Methyl-1H-indole-5-carbaldehyde is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,90923-75-4
Take (100mg, 0.535mmol)3-Bromo-1,2-phenylenediamine is dissolved in 5 mL of absolute ethanol,Add (102 mg, 0.641 mmol) 1-methylindole-5-aldehyde, (13.81 mg, 0.080 mmol) p-toluenesulfonic acid, and reflux for 24 h.The reaction was monitored by TLC. After the reaction was completed, the reaction solution was concentrated, and the concentrate was extracted with ethyl acetate-water.The ethyl acetate layer was dried over anhydrous sodium sulfate and concentrated.After column chromatography of petroleum ether-ethyl acetate 2: 1, 120 mg of solid was obtained with a yield of 68.8%.
90923-75-4 1-Methyl-1H-indole-5-carbaldehyde 7537534, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Patent; Southern Medical University; Chen Jianjun; Ren Yichang; Cheng Binbin; (19 pag.)CN110551104; (2019); A;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles