91348-45-7, Ethyl 3-bromo-1H-indole-2-carboxylate is a indole-building-block compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,91348-45-7
General procedure: To a mechanically stirred mixture of (1) (27.97 mmol),K2CO3 (83.91 mmol) and dry DMF (50 mL), benzyl bromideor 4-chlorobenzyl bromide (30.77 mmol) was addeddropwise respectively. After stirring for 48 h, the solutionwas filtered and the filtrate was extracted with ethyl acetate(3 ¡Á 20 mL). The combined organic extracts were washedwith water (50 mL) and brine (50 mL), dried over sodiumsulfate and concentrated. The crude product was purified bycolumn chromatography using a mixture of ethyl acetate/hexane (20:80) as eluent to give the title compounds (2a/b).
91348-45-7 Ethyl 3-bromo-1H-indole-2-carboxylate 4715017, aindole-building-block compound, is more and more widely used in various fields.
Reference£º
Article; Kaur, Jeewanjot; Singh, Amanjot; Singh, Gagandeep; Verma, Raman K.; Mall, Rajiv; Medicinal Chemistry Research; vol. 27; 3; (2018); p. 903 – 914;,
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles