I found the field of Chemistry; Pharmacology & Pharmacy very interesting. Saw the article Bioinspired benzoxanthene lignans as a new class of antimycotic agents: synthesis and Candida spp. growth inhibition published in 2020. Quality Control of Benzyl Alcohol, Reprint Addresses Genovese, C (corresponding author), Univ Catania, Dept Biomed & Biotechnol Sci, Microbiol Sect, Catania, Italy.. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol
In this work we synthetized the bioinspired benzoxanthene lignans (BXLs)3,14-22, and the phenazine derivative23as potential antimycotic agents. MICs and MFCs againstCandidastrains were determined. In a preliminary screening, compounds3,15,20,21,22were substantially inactive. Compounds14and17showed antifungal activity, being able to inhibit the growth of the majority ofCandidastrains with MIC values in the range 4.6-19.2 mu M (14) and 26.0-104.3 mu M (17); for three strains, the MICs were lower than those obtained using the antimycotic drug fluconazole. The three BXLs18,19and23showed some MIC values lower than that of fluconazole;18was also active against two non-albicans Candidastrains resistant to fluconazole. Phenazine23, although active only against one strain (MIC = 1.3 mu M), was one order of magnitude more potent than fluconazole. All the BXLs were fungicidal.
Quality Control of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Genovese, C; Pulvirenti, L; Cardullo, N; Muccilli, V; Tempera, G; Nicolosi, D; Tringali, C or concate me.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles