An article Synthesis of Homoallylic Alcohols with Acyclic Quaternary Centers through Co-III-Catalyzed Three-Component C-H Bond Addition to Internally Substituted Dienes and Carbonyls WOS:000479782900001 published article about ENANTIOSELECTIVE SYNTHESIS; STEREOGENIC CENTERS; FUNCTIONALIZATION; STEREOCENTERS; SYSTEMS; CONSTRUCTION; ACTIVATION in [Sun Dongbang; Shen, Zican; Ellman, Jonathan A.] Yale Univ, Dept Chem, 225 Prospect St, New Haven, CT 06520 USA in 2019.0, Cited 49.0. Application In Synthesis of 3-Hydroxybenzaldehyde. The Name is 3-Hydroxybenzaldehyde. Through research, I have a further understanding and discovery of 100-83-4
An efficient Co-III-catalyzed three-component strategy to prepare homoallylic alcohols containing acyclic quaternary centers is disclosed. This transformation enables the introduction of two C-C sigma bonds through C-H bond activation and sequential addition to internally substituted dienes and a wide range of aldehydes and activated ketones. Isoprene and other internally monosubstituted dienes are effective inputs, with the reaction proceeding with high diastereoselectivity for those substrate combinations that result in more than one stereogenic center. Moreover, the opposite relative stereochemistry can be achieved by employing 1,2-disubstituted dienes. A mechanism for the transformation is proposed based upon the relative stereochemistry of the products and studies with isotopically labeled starting materials.
Application In Synthesis of 3-Hydroxybenzaldehyde. About 3-Hydroxybenzaldehyde, If you have any questions, you can contact Sun, DB; Shen, ZC; Ellman, JA or concate me.
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Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles