28166-41-8, Name is α-Cyano-4-hydroxycinnamic Acid, molecular formula is C10H7NO3, SDS of cas: 28166-41-8, belongs to indole-building-block compound, is a common compound. In a patnet, author is Shan, Xiang-Huan, once mentioned the new application about 28166-41-8.
In this work, CuSO4 is utilized as a practical redox catalyst for tandem dual annulation in the synthesis of indole-fused tetracyclic heteroacenes, which are important skeletons in both medicinal chemistry and materials chemistry. The preparation of such skeletons in a convenient and efficient manner is in high demand. This method realizes the modular synthesis of benzofuro-, benzothieno-, and indoloindoles from abundant feedstocks such as 2-halobenzyl halides and nitrile derivatives in up to 99% yields, providing a rapid access to diverse indole-fused heteroacenes with biological or optoelectronic properties.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 28166-41-8 help many people in the next few years. SDS of cas: 28166-41-8.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles