A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Product Details of 5192-23-4, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 5192-23-4, Name is 4-Aminoindole, molecular formula is C8H8N2. In a Article, authors is Dushin, Russell G.£¬once mentioned of 5192-23-4
Synthesis and PKCtheta inhibitory activity of a series of 4-indolylamino-5-phenyl-3-pyridinecarbonitriles
A series of 4-indolylamino-5-phenyl-3-pyridinecarbonitrile inhibitors of PKCtheta were synthesized as potential anti-inflammatory agents. The effects of specific substitution on the 5-phenyl moiety and variations of the positional isomers of the 4-indolylamino substituent were explored. This study led to the discovery of compound 12d, which had an IC50 value of 18 nM for the inhibition of PKCtheta.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 5192-23-4, help many people in the next few years.Product Details of 5192-23-4
Reference£º
Indole alkaloid derivatives as building blocks of natural products from?Bacillus thuringiensis?and?Bacillus velezensis?and their antibacterial and antifungal activity study,
Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles