Chemo-enzymatic cascade processes are invaluable due to their ability to rapidly construct high-value products from available feedstock chemicals in a one-pot relay manner. In an article, author is Thombal, Raju S., once mentioned the application of 69-79-4, Name is Maltose, molecular formula is C12H22O11, molecular weight is 342.2965, MDL number is MFCD00135877, category is indole-building-block. Now introduce a scientific discovery about this category, Quality Control of Maltose.
A Pd(II)-catalyzed C(sp(3))-H/C(sp(2))-H coupling/annulation of anilides and a-dicarbonyl compounds for the synthesis of diverse N-acyl indoles is described. The reaction is achieved by cascade C-H activation, coupling, and intramolecular cyclization. This protocol provides a variety of indoles with high functional group tolerance and excellent regioselectivity. The utility of this protocol is demonstrated by transforming the synthesized compound into diversely functionalized analogues.
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Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles