Category: 100-51-6

Authors Mpitimpiti, AN; Petzer, JP; Petzer, A; Jordaan, JHL; Lourens, ACU in SPRINGER published article about PARKINSONS-DISEASE; IMMUNOSTIMULATORY ACTIVITY; COUMARIN DERIVATIVES; HIGH-POTENCY; 3-FORMYL-4-HYDROXYCOUMARIN; CONSTITUENTS; SAFINAMIDE; SCAFFOLD in [Mpitimpiti, Annah N.; Petzer, Jacobus P.; Petzer, Anel; Lourens, Anna C. U.] North West Univ, Ctr Excellence Pharmaceut Sci, Private Bag X6001, ZA-2520 Potchefstroom, South Africa; [Petzer, Jacobus P.; Petzer, Anel; Lourens, Anna C. U.] North West Univ, Sch Pharm, Pharmaceut Chem, Private Bag X6001, ZA-2520 Potchefstroom, South Africa; [Jordaan, Johannes H. L.] North West Univ, Res Focus Area Chem Resource Beneficiat, Private Bag X6001, ZA-2520 Potchefstroom, South Africa in 2019.0, Cited 57.0. Recommanded Product: Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Based on reports that chromone compounds are good potency inhibitors of monoamine oxidase (MAO), the present study evaluates the effect of substitution with flexible side chains on the 3 position on MAO inhibition potency. Fifteen chromone derivatives were synthesised by reacting aromatic and aliphatic amines and alcohols with chromone 3-carboxylic acid in the presence of carbonyldiimidazole (CDI). This yielded chromane-2,4-dione and ester chromone derivatives. Generally, the esters exhibited weak MAO inhibition, while the chromane-2,4-dione derivatives showed promise as selective MAO-B inhibitors with IC50 values in the micromolar range. Compound 14b, 3-[(benzylamino)methylidene]-3,4-dihydro-2H-1-benzopyran-2,4-dione, was the most potent MAO-B inhibitor with an IC50 value of 638 mu M. This compound was shown to be a reversible and competitive MAO-B inhibitor with a K-i of 94 mu M. In conclusion, the effect of chain elongation and introduction of flexible substituents on position 3 of chromone were explored and the results showed that aminomethylidene substitution is preferable over ester substitution. Good potency MAO-B inhibitors may act as leads for the design and development of therapy for Parkinson’s disease where these agents reduce the central metabolism of dopamine. [GRAPHICS] .

About Benzyl Alcohol, If you have any questions, you can contact Mpitimpiti, AN; Petzer, JP; Petzer, A; Jordaan, JHL; Lourens, ACU or concate me.. Recommanded Product: Benzyl Alcohol

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Sousa, SCA; Realista, S; Royo, B in [Sousa, Sara C. A.; Realista, Sara; Royo, Beatriz] Univ Nova Lisboa, Inst Tecnol Quim & Biol Antonio Xavier, ITQB NOVA, Oeiras, Portugal published Bench-Stable Manganese NHC Complexes for the Selective Reduction of Esters to Alcohols with Silanes in 2020.0, Cited 58.0. Name: Benzyl Alcohol. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

Selective reduction of esters to alcohols was accomplished through Mn(I)-mediated hydrosilylation reaction. The manganese tricarbonyl complex [Mn(bis-NHC)(CO)(3)Br] resulted an active pre-catalyst for the reduction of a variety of esters using phenylsilane and the cheap and readily available polymethylhydrosiloxane. Anin situexamination of the catalytic reaction using(55)Mn NMR spectroscopy allowed us to detect the formation of Mn(I) intermediate active species.

Name: Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Sousa, SCA; Realista, S; Royo, B or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

COA of Formula: C7H8O. Wu, JQ; Hua, WM; Yue, YH; Gao, Z in [Wu, Jiequn; Hua, Weiming; Yue, Yinghong; Gao, Zi] Fudan Univ, Shanghai Key Lab Mol Catalysis & Innovat Mat, Dept Chem, Shanghai 200438, Peoples R China published A Highly Efficient Bifunctional Catalyst CoOx/tri-g-C(3)N(4)for One-Pot Aerobic Oxidation-Knoevenagel Condensation Reaction in 2020.0, Cited 43.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

A highly efficient bifunctional catalyst of an s-triazine-based carbon-nitride-supported cobalt oxide is developed for the aerobic oxidation-Knoevenagel condensation tandem reaction of benzyl alcohol and malononitrile, whereby 96.4% benzyl alcohol conversion with nearly 100% selectivity towards benzylmalononitrile can be obtained in 6 h at 80 degrees C. The excellent catalytic performance derives from the high basicity of carbon nitride and strong redox ability of Co species induced by carbon nitride. The catalyst is also quite stable and can be reused without any regeneration treatment, whose product yield is only an 11.5% reduction after four runs.

COA of Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact Wu, JQ; Hua, WM; Yue, YH; Gao, Z or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: 100-51-6. Recently I am researching about 1-DEOXY-D-XYLULOSE 5-PHOSPHATE SYNTHASE; BENZOIC-ACID BIOSYNTHESIS; TERPENE SYNTHASES; FLORAL SCENT; LINALOOL SYNTHASE; FUNCTIONAL-CHARACTERIZATION; (E)-BETA-OCIMENE SYNTHASE; ARABIDOPSIS-THALIANA; MYRCENE SYNTHASE; GENE-EXPRESSION, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31572165]. Published in WILEY in HOBOKEN ,Authors: Tian, JP; Ma, ZY; Zhao, KG; Zhang, J; Xiang, L; Chen, LQ. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

Wintersweet (Chimonanthus praecox L.) is an important ornamental plant in China with a pleasant floral scent. To explore the potential mechanisms underlying differences in the fragrances among genotypes of this plant, we analyzed floral volatile organic compounds (VOCs) from two different genotypes: SW001, which has little to no fragrance, and the scented genotype H29. The major VOCs in H29 were linalool, trans-beta-ocimene, benzyl acetate, methyl salicylate, benzyl alcohol (BAlc) and methyl benzoate. The most important aroma-active compound in H29, linalool, was emitted at a low concentration in SW001, which had markedly higher levels of trans-beta-ocimene than H29. Next, to investigate scent biosynthesis, we analyzed the transcriptome and proteome of fully open flowers of the two genotypes. A total of 14 443 differentially expressed unigenes and 196 differentially expressed proteins were identified. Further analyses indicated that 56 differentially expressed genes involved in the terpenoid and benzenoid biosynthesis pathways might play critical roles in regulating floral fragrance difference. Disequilibrium expression of four terpene synthase genes resulted in diverse emission of linalool and trans-beta-ocimene in both genotypes. In addition, the expressions of two CpMYC2 transcription factors were both upregulated in H29, implying that they may regulate linalool production. Notably, 16 of 20 genes in the benzenoid biosynthesis pathway were downregulated, corresponding to the relatively low level of benzenoid production in SW001. The lack of benzyl acetate might indicate that SW001 may lack substrate BAlc or functional acetyl-CoA:benzylalcohol acetyltransferase.

About Benzyl Alcohol, If you have any questions, you can contact Tian, JP; Ma, ZY; Zhao, KG; Zhang, J; Xiang, L; Chen, LQ or concate me.. Recommanded Product: 100-51-6

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Recommanded Product: Benzyl Alcohol. In 2019.0 MATER TODAY-PROC published article about GOLD NANOPARTICLES; GREEN SYNTHESIS; EXTRACT in [Warghane, Umesh K.; Dhankar, Raksha P.] Sardar Patel Mahavidyalaya, Dept Chem, Ctr Higher Learning & Res, Chandrapur 442402, Maharashtra, India in 2019.0, Cited 12.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

In the present investigation, green synthesis of silver nanoparticles from plant extract of Ehretia laevis have been studied for their catalytic performance towards the oxidation of alcohols containing aromatic ring into the corresponding aldehydes. The synthesis of nanoparticles and purity was confirmed by UV-visible analysis, scanning electron microscopy (SEM), transmission electron microscope analysis (TEM) and XRD analysis. SEM analysis showed cubical and relatively uniform shape of nanoparticles and XRD analysis revealed the face centred cubic system and crystalline nature of silver nanoparticle (AgNPs). The excellent catalytic oxidation process of aromatic alcohols by silver nanoparticles offered the merit of being a short reaction time, efficient, easy and clean synthetic path. The remarkable activity of the catalyst was exhibited without the significant loss. The catalytic route suggests the notable features of green approach, higher yields and recyclability. (C) 2019 Elsevier Ltd. All rights reserved.

Recommanded Product: Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Warghane, UK; Dhankar, RP or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Safety of Benzyl Alcohol. Authors Choudhury, P; Behera, PK; Bisoyi, T; Sahu, SK; Sahu, RR; Prusty, SR; Stitgen, A; Scanlon, J; Kar, M; Rout, L in ROYAL SOC CHEMISTRY published article about in [Choudhury, Prabhupada; Behera, Pradyota Kumar; Bisoyi, Tanmayee; Sahu, Santosh Kumar; Sahu, Rashmi Ranjan; Prusty, Smruti Ranjita; Rout, Laxmidhar] Berhampur Univ, Dept Chem, Berhampur 760007, Odisha, India; [Stitgen, Abigail; Scanlon, Joseph] Ripon Coll, Dept Chem, Wisconsin Rapids, WI 54971 USA; [Sahu, Rashmi Ranjan; Kar, Manoranjan] IIT Patna, Dept Phys, Patna, Bihar, India; [Rout, Laxmidhar] Indian Inst Sci Educ & Res, Sch Chem Sci, Berhampur 760007, Odisha, India in 2021, Cited 25. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Herein, we report a new protocol for the dehydrogenative oxidation of aryl methanols using the cheap and commercially available catalyst CuSeO3 center dot 2H(2)O. Oxygen-bridged [Cu-O-Se] bimetallic catalysts are not only less expensive than other catalysts used for the dehydrogenative oxidation of aryl alcohols, but they are also effective under mild conditions and at low concentrations. The title reaction proceeds with a variety of aromatic and heteroaromatic methanol examples, obtaining the corresponding carbonyls in high yields. This is the first example using an oxygen-bridged copper-based bimetallic catalyst [Cu-O-Se] for dehydrogenative benzylic oxidation. Computational DFT studies reveal simultaneous H-transfer and Cu-O bond breaking, with a transition-state barrier height of 29.3 kcal mol(-1).

Safety of Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Choudhury, P; Behera, PK; Bisoyi, T; Sahu, SK; Sahu, RR; Prusty, SR; Stitgen, A; Scanlon, J; Kar, M; Rout, L or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

HPLC of Formula: C7H8O. In 2021.0 CHINESE J CHEM published article about PALLADIUM-CATALYZED ARYLATION; HECK COUPLING REACTION; 2,5-FURANDICARBOXYLIC ACID; SUZUKI REACTION; BIOMASS; HALIDES; FURAN; NANOPARTICLES; CONVERSION; CHEMICALS in [Xie, Yi; Yu, Bin; Luo, Jiajun; Yin, Biaolin; Jiang, Huanfeng] South China Univ Technol, Sch Chem & Chem Engn, Key Lab Funct Mol Engn Guangdong Prov, Guangzhou 510640, Guangdong, Peoples R China in 2021.0, Cited 69.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6.

Main observation and conclusion Herein, we describe an environmentally benign and cost-effective protocol for the synthesis of valuable bifuranyl dicarboxylates, starting with alpha-bromination of readily accessible furan-2-carboxylates by LiBr and K2S2O8. Furthermore, the bromination intermediate product 5-bromofuran-2-carboxylates were then conducted in a palladium-catalyzed reductive homocoupling reactions in the presence of alcohols to afford bifuranyl dicarboxylates. One of the final products in this protocol, [2,2′]bifuran-5,5′-dicarboxylic acid esters, are essential monomers of poly(ethylene bifuranoate), which can be served as an green and versatile alternative polymer for traditional poly(ethylene terephthalate) that is currently common in technical plastics.

About Benzyl Alcohol, If you have any questions, you can contact Xie, Y; Yu, B; Luo, JJ; Yin, BL; Jiang, HF or concate me.. HPLC of Formula: C7H8O

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Name: Benzyl Alcohol. Authors Arcas, R; Peris, E; Mas-Marza, E; Fabregat-Santiago, F in ROYAL SOC CHEMISTRY published article about in [Arcas, Ramon; Peris, Eduardo; Mas-Marza, Elena; Fabregat-Santiago, Francisco] Univ Jaume 1, Inst Adv Mat INAM, Av Vicente Sas Baynat S-N, E-12006 Castellon de La Plana, Spain in 2021, Cited 44. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6

Photoelectrochemical approaches are finding use in the transformation of organic molecules beyond water oxidation and CO2 reduction. Among the different reactions that can be performed, the selective oxidation of alcohols to aldehydes is a transformation of great interest, as aldehydes are the starting materials for the preparation of more complex organic molecules with high added value. In order to develop efficient photoelectrochemical methodologies for this reaction, it is crucial to reveal all the different parameters that are involved in such light-driven processes. Herein we analyse in detail the effect of the light wavelength and atmosphere on the photoelectrochemical oxidation of benzyl alcohol to benzaldehyde using BiVO4 electrodes. Our studies demonstrate that an important contribution to the oxidation of alcohol is due to UV light-induced production of singlet oxygen, which is also responsible for the formation of hydrogen peroxide in the reaction media. These findings are key for identifying and evaluating the underlying mechanism involved in this type of photoelectrochemically induced oxidation, in order to avoid misinterpretations of the efficiencies.

Name: Benzyl Alcohol. About Benzyl Alcohol, If you have any questions, you can contact Arcas, R; Peris, E; Mas-Marza, E; Fabregat-Santiago, F or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

Product Details of 100-51-6. Recently I am researching about CROSS-COUPLING REACTIONS; DIARYLMETHYL CARBONATES; DECARBOXYLATIVE BENZYLATION; ASYMMETRIC BENZYLATION; DIMETHYL MALONATE; GRIGNARD-REAGENTS; ALPHA-BENZYLATION; ARYLBORONIC ACIDS; PALLADIUM; ALKYLATION, Saw an article supported by the Research Grant of Institute of Natural Sciences at Nihon University; Japan Society for the Promotion of ScienceMinistry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science [17K05794]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Tsuji, H; Hashimoto, K; Kawatsura, M. The CAS is 100-51-6. Through research, I have a further understanding and discovery of Benzyl Alcohol

The nickel-catalyzed benzylic substitution of benzyl alcohol derivatives with a soft carbon nucleophile is extremely rare compared to that with a hard carbon nucleophile. We have achieved the nickel-catalyzed benzylic substitution of benzyl esters with malonates as a soft carbon nucleophile. Primary and secondary benzyl 2,3,4,5,6-penta-fluorobenzoates as well as a wide variety of malonate derivatives were well tolerated in the nickel-catalyzed reaction, providing the corresponding alkylation products in 46-86% yields (34 examples). Additionally, we propose a possible reaction mechanism that would undergo via the eta(1)- and eta(3)-benzylnickel intermediates.

Product Details of 100-51-6. About Benzyl Alcohol, If you have any questions, you can contact Tsuji, H; Hashimoto, K; Kawatsura, M or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles

In 2020.0 J AM CHEM SOC published article about CROSS-COUPLING REACTIONS; UNACTIVATED ALKENES; AMINO-ACIDS; HYDROCARBOFUNCTIONALIZATION; PHOSPHONATES; PALLADIUM; ARYLATION; REAGENTS; LIGANDS in [He, Shi-Jiang; Wang, Jia-Wang; Li, Yan; Xu, Zhe-Yuan; Wang, Xiao-Xu; Lu, Xi; Fu, Yao] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, CAS Key Lab Urban Pollutant Convers, iChEM,Anhui Prov Key Lab Biomass Clean Energy, Hefei 230026, Peoples R China in 2020.0, Cited 68.0. The Name is Benzyl Alcohol. Through research, I have a further understanding and discovery of 100-51-6. COA of Formula: C7H8O

Substantial advances in enantioconvergent C(sp(3))-C(sp(3)) bond formation reactions have been made in recent years through the use of transition-metal-catalyzed cross-coupling reactions of racemic secondary alkyl electrophiles with organometallic reagents. Herein, we report a general process for the asymmetric construction of alkyl-alkyl bonds adjacent to heteroatoms, namely, a nickel-catalyzed enantioconvergent reductive hydroalkylation of olefins with alpha-heteroatom phosphorus or sulfur alkyl electrophiles. Including the use of readily available olefins, this reaction has considerable advantages, such as mild reaction conditions, a broad substrate scope, and good functional group compatibility, making it a desirable alternative to traditional electrophile-nucleophile cross-coupling reactions.

COA of Formula: C7H8O. About Benzyl Alcohol, If you have any questions, you can contact He, SJ; Wang, JW; Li, Y; Xu, ZY; Wang, XX; Lu, X; Fu, Y or concate me.

Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles