Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Recommanded Product: Dihydrothiophen-3(2H)-one, 1003-04-9, Name is Dihydrothiophen-3(2H)-one, SMILES is O=C1CSCC1, belongs to indole-building-block compound. In a document, author is Xie, Lihua, introduce the new discover.
The chiral amide-guanidine-catalyzed asymmetric formal [3+2] cycloaddition of isatogens with azlactones is presented. This strategy provided a facile and feasible route to chiral indolin-3-one derivatives bearing two contiguous tetrasubstituted stereocenters in moderate to good yields with high diastereoselectivities and enantioselectivities. A possible working mode was proposed to elucidate the chiral control of the process.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 1003-04-9. Recommanded Product: Dihydrothiophen-3(2H)-one.
Reference:
Indole alkaloid derivatives as building blocks of natural products from Bacillus thuringiensis and Bacillus velezensis and their antibacterial and antifungal activity study,
,Preparation of Indole Containing Building Blocks for the Regiospecific Construction of Indole Appended Pyrazoles and Pyrroles